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Pulmonology / Infectious Disease

CURB-65 Score Calculator

Severity assessment for community-acquired pneumonia (CAP). Guides outpatient vs ward vs ICU disposition per BTS, IDSA/ATS, and Indian Chest Society (ICS) guidelines.

CURB-65 Score

0/5

30-day mortality: 0.7%

Disposition

Low risk — Outpatient treatment

Empiric Antibiotic (ICS India 2012)

Oral antibiotics at home. Per ICS India: Amoxicillin 1g TDS × 5–7d (₹40–₹80). Macrolide (azithromycin 500mg OD × 3d, ₹50) if atypical suspected or penicillin allergy. Re-review at 48–72 hrs.

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Also Known As

CURB-65 scoreCURB65 calculatorCRB-65 scorecommunity acquired pneumoniaCAP severity scorepneumonia admission criteriapneumonia ICU criteriaBTS pneumonia guidelinesIDSA ATS pneumonia 2019ICS India pneumoniapneumonia mortality calculatorazithromycin pneumoniaceftriaxone pneumoniaamoxicillin CAP Indiapneumonia outpatient

What is the CURB-65 score?

The CURB-65 score is a five-point severity assessment for adults presenting with community-acquired pneumonia (CAP). Developed by Lim et al. (Thorax, 2003) from the British Thoracic Society's CAP study, it estimates 30-day mortality and helps decide whether a patient should be treated as an outpatient, on a general ward, or in the ICU.

CURB-65 is simpler than the PSI/PORT score (only 5 variables vs 20), making it ideal for the OPD, ED, or first-contact GP setting. A bedside variant, CRB-65, omits urea — useful when no labs are available.

Score Components (mnemonic: CURB-65)

  • C — Confusion (new, or AMTS ≤ 8)
  • U — Urea > 7 mmol/L (BUN > 19 mg/dL or ~ blood urea > 40 mg/dL)
  • R — Respiratory rate ≥ 30/min
  • B — Blood pressure (SBP < 90 or DBP ≤ 60 mmHg)
  • 65 — Age ≥ 65 years

Disposition by Score (BTS + ICS India)

  • 0–1: Low mortality (<3%) — outpatient treatment. Oral amoxicillin ± macrolide.
  • 2: Moderate risk (9%) — hospitalise, consider short-stay or ward.
  • 3–5: High risk (15–57%) — inpatient with strong consideration of ICU/HDU.

Always override the score if SpO₂ < 92% on room air, bilateral/multilobar infiltrates, lactate > 2, decompensated comorbidity, or unreliable home situation.

Empirical Antibiotics — ICS India + ICMR AMR 2022

  • Outpatient: Amoxicillin 1g TDS × 5–7d (~₹60 course) ± Azithromycin 500mg OD × 3d (~₹50).
  • Ward: Co-amoxiclav 1.2g IV TDS (~₹270/day) + Azithromycin 500mg OD IV/PO.
  • ICU: Ceftriaxone 2g IV OD (~₹120/day) + Azithromycin 500mg OD; OR Piperacillin-tazobactam 4.5g Q8H (~₹1,350/day) if Pseudomonas risk (structural lung disease, prior IV antibiotics, recent hospitalisation).
  • Atypical cover: Macrolide or doxycycline (₹15/day) — essential in India due to high Mycoplasma/Chlamydia/Legionella rates.
  • Influenza season: Add oseltamivir 75mg BD × 5d (~₹500 course) empirically when ILI prevalence is high.

When NOT to use CURB-65

  • Hospital-acquired or ventilator-associated pneumonia (HAP/VAP) — use IDSA HAP/VAP criteria.
  • Immunocompromised hosts (HIV, post-transplant, neutropenia, on biologics).
  • Aspiration pneumonia in nursing-home residents (use a broader antibiotic spectrum).
  • Active pulmonary TB — high prevalence in India; always screen with sputum AFB/CBNAAT.
  • Severe COVID-19 pneumonia — use 4C Mortality, WHO clinical progression, or NEWS2 instead.

Frequently Asked Questions

What is the difference between CURB-65 and CRB-65?

CRB-65 drops the urea variable, making it suitable for primary care or rural OPD where labs are not immediately available. Mortality risk increases at CRB-65 ≥ 1 (refer) and ≥ 2 (urgent admission).

My patient has SpO₂ 88% on room air but CURB-65 is 0 — outpatient OK?

No. CURB-65 does not include oxygenation. Any patient with SpO₂ < 92% on room air should be admitted regardless of CURB-65 — this is an explicit ICS India and BTS over-ride.

Why is BUN > 19 mg/dL but Indian labs report blood urea?

Indian labs typically report blood urea, not BUN. Blood urea > 42 mg/dL (= 7 mmol/L) meets the cut-off. Some texts use blood urea > 40 mg/dL as a practical threshold.

What antibiotic course duration in India?

ICS India and ICMR 2022 recommend 5 days for mild CAP if afebrile by 48–72 hours and clinically stable. Severe/bacteremic CAP, S. aureus, or Pseudomonas: 7–14 days. Longer courses do not reduce relapse and drive resistance.

Should I use CURB-65 or PSI/PORT?

PSI is more accurate for identifying truly low-risk patients (PSI class I–II safe to discharge), but it has 20 variables. CURB-65 is faster, simpler, and equally good at identifying high-risk patients. Most Indian EDs use CURB-65 as the default; PSI as a secondary check before discharge.

Does CURB-65 work for COVID-19 pneumonia?

It under-estimates severity in COVID-19 because hypoxia is the dominant feature, not BP or confusion. Use the 4C Mortality Score, NEWS2, or simply SpO₂/FiO₂ ratio for COVID-19 triage.

Clinical Disclaimer: CURB-65 was derived in adults with confirmed CAP — not for hospital-acquired pneumonia, immunocompromised hosts, or non-pneumonia sepsis. Always integrate clinical judgement, social factors (lives alone, comorbidities), and oxygenation (SpO₂ < 92%) when making the admission call. Always verify against your local prescribing reference and apply clinical judgment.

References

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